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| Title: |
A New Sesquiterpene from the Endophytic Fungus Nigrospora sphaerica #003 |
| First Author: |
Chen, Ziming; Dong, Zejun; Wen, Jing; Feng, Tao; Liu, Jikai |
| Abstract: |
A new drimane sesquiterpene, 3 beta-OH-dendocarbin A (1), together with six known sesquiterpenes (27), were isolated from endophytic fungus Nigrospora sphaerica #003. The structure of 1 was elucidated by MS, 1D and 2D-NMR data analyses, and comparison data with those of known compounds. Compounds 1-7 were tested the cytotoxicity against five tumor cell lines (HL-60, A-549, SMMC-7721, MCF-7 and SW-480). However, none of them showed obvious activities, with IC50 > 40 mu M. |
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| Page Number: |
307-310 |
| Issue: |
3 |
| Subject: |
Plant Sciences |
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| PubYear: |
2016 |
| Volume: |
10 |
| Publication Name: |
RECORDS OF NATURAL PRODUCTS |
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