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论文题目: |
7-O-Methylkaempferol and -quercetin Glycosides from the Whole Plant of Nervilia fordii
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论文题目英文: |
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作者: |
Tian, Li-Wen; Pei, Ying; Zhang, Ying-Jun; Wang, Yi-Fei; Yang, Chong-Ren
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论文出处: |
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年: |
2009
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卷: |
72 |
期: |
6 |
页: |
1057-1060 |
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发表期刊: |
JOURNAL OF NATURAL PRODUCTS |
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影响因子: |
2.843
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摘要: |
Five new 7-O-methylkaempferol and -quercetin glycosides, namely, nervili fordins A-E (1-5), were isolated from the whole plant of Nervilia fordii, together with seven known flavonoids (6, 7, and 9-13) and one known coumarin (8). Their structures were elucidated on the basis of extensive spectroscopic analyses, including HSQC, HMBC, ROESY, and chemical methods. Compounds 1-3 and 6-13 were evaluated for their anti-herpes simplex virus 1 (HSV-1) activity and cytotoxicity on African green monkey kidney cells (Vero cells) in vitro. Of the tested compounds, only esculetin (8) exhibited antiviral activity against HSV-1, while the aglycones (11-13) showed stronger cytotoxicity on Vero cells than their glycosides (1-3, 6, and 7). |
英文摘要: |
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