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论文 |
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论文题目: |
Isolation of Chemical Constituents from the Aerial Parts of Verbascum thapsus and Their Antiangiogenic and Antiproliferative Activities
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论文题目英文: |
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作者: |
Zhao, Yan-Li; Wang, Si-Feng; Li, Yang; He, Qiu-Xia; Liu, Ke-Chun; Yang, Yong-Ping; Li, Xiao-Li
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论文出处: |
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年: |
2011
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卷: |
34 |
期: |
5 |
页: |
703-707 |
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发表期刊: |
ARCHIVES OF PHARMACAL RESEARCH |
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影响因子: |
1.074
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摘要: |
Phytochemical investigation of Verbascum thapsus led to the isolation and identification of one new iridoid compound named verbathasin A, along with ten known compounds. The structure and relative stereochemistry of verbathasin A were elucidated by analysis of spectroscopic data. All the isolates except 10-deoxyeucommiol and ajugol were tested for antiangiogenic and antiproliferative activities, and compounds luteolin and 3-O-fucopyranosylsaikogenin F showed promising antiproliferative activities, with an obvious effect of inducing apoptosis of A549 lung cancer cells. |
英文摘要: |
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