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论文 |
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论文题目: |
Przewalskone: a cytotoxic adduct of a danshenol type terpenoid and an icetexane diterpenoid via hetero-Diels-Alder reaction from Salvia przewalskii
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论文题目英文: |
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作者: |
Xu, Gang; Yang, Xing-Wei; Wu, Chun-Yan; Li, Xiao-Nian; Su, Jia; Deng, Xu; Li, Yan; Qin, Hong-Bo; Yang, Li-Xin; Zhao, Qin-Shi
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论文出处: |
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年: |
2012
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卷: |
48 |
期: |
37 |
页: |
4438-4440 |
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发表期刊: |
CHEMICAL COMMUNICATIONS |
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影响因子: |
5.787
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摘要: |
Przewalskone (1), an unprecedented adduct of two different terpenoid units via a hetero-Diels-Alder cycloaddition, was isolated from the roots of Salvia przewalskii. The structure and absolute configurations were elucidated by extensive analysis of NMR spectra and crystal X-ray diffractions. Compound 1 exhibited significant cytotoxicities against five human cancer lines in vitro (IC50 0.69-2.35 mu M). |
英文摘要: |
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