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论文 |
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论文题目: |
Limonoids from the leaves of Toona ciliata var. yunnanensis
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论文题目英文: |
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作者: |
Liu, Jie-Qing; Wang, Cui-Fang; Li, Yan; Chen, Jian-Chao; Zhou, Lin; Qiu, Ming-Hua
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论文出处: |
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年: |
2012
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卷: |
76 |
期: |
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页: |
141-149 |
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发表期刊: |
PHYTOCHEMISTRY |
第一作者所在部门: |
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收录类别: |
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影响因子: |
2.946
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摘要: |
Twelve limonoids, toonayunnanins A-L (1-12) and eleven known compounds (13-23) were isolated from the leaves of Toona ciliata var. yunnanensis, and their structures were elucidated by means of extensive spectroscopic analyses, particularly 1D and 2D NMR techniques. The inhibitory effects of all the isolated compounds were evaluated on human tumor cell lines, such as HL-60, SMMC-7721, A-549, MCF-7 and SW480. Cedrelone (13) and dysobinin (18) showed significant cytotoxicity, and toonayunnanin B (2) and epoxyazadiradione (14), were found to be slightly cytotoxic against the above cell lines. Furthermore, this study provides valuable information for the chemotaxonomy of T. ciliata varieties. (C) 2012 Elsevier Ltd. All rights reserved. |
英文摘要: |
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