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论文 |
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论文题目: |
Mekongenines A and B, two new alkaloids from Bousigonia mekongensis
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论文题目英文: |
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作者: |
Fu, Yanhui; He, Hongping; Di, Yingtong; Li, Shunlin; Zhang, Yu; Hao, Xiaojiang
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论文出处: |
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年: |
2012
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卷: |
53 |
期: |
28 |
页: |
3642-3646 |
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发表期刊: |
TETRAHEDRON LETTERS |
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影响因子: |
2.538
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摘要: |
Mekongenine A (1) possessing an unprecedented structure constituted from the union of a rare 2,7-seco eburnamine half and an aspidospermine alkaloid, together with a new bisindole alkaloid, mekongenine B (2), consisting of an eburnamine-aspidospennine type skeleton, was isolated from Bousigonia mekongensis. Their structures were elucidated by means of spectroscopic methods and those of 2 were further confirmed by X-ray diffraction. The absolute configurations of 1 and 2 were determined by comparison of quantum chemical TDDFT calculated and experimental ECD spectra. Mekongenines A (1) and B(2) exhibited cell growth inhibitory activities against various human cancer cell lines. (C) 2012 Elsevier Ltd. All rights reserved. |
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