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论文 |
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论文题目: |
Methyl Pothoscandensate, a New ent-18(4 -> 3)-Abeokaurane from Pothos scandens
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论文题目英文: |
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作者: |
Liu, Hong-Xin; Bi, Jun-Long; Wang, Yue-Hu; Gu, Wei; Su, Yao; Liu, Fang; Yang, Shi-Xian; Hu, Guang-Wan; Luo, Ji-Feng; Yin, Ge-Fen; Long, Chun-Lin
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论文出处: |
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年: |
2012
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卷: |
95 |
期: |
7 |
页: |
2468 |
联系作者: |
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发表期刊: |
HELVETICA CHIMICA ACTA |
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影响因子: |
1.396
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摘要: |
Methyl pothoscandensate (1), a new molecular skeleton of ent-18(4?3)-abeokaurane, along with eight known compounds was isolated from the whole plant of Pothos scandens. The structure of the new compound was established by spectroscopic techniques and confirmed by single-crystal X-ray diffraction. The inhibitory activity of selected compounds against porcine respiratory and reproductive syndrome virus (PRRSV) was measured by the cytopathic effect (CPE) method. Compound 1 showed weak effect on PRRSV with an IC50 value of 40.3 +/- 8.3 mu M (TI=15.7). |
英文摘要: |
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