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论文 |
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论文题目: |
Chemical constituents of Euphorbia tangutica
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论文题目英文: |
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作者: |
Zhang, Ben-Yin; Wang, Huan; Luo, Xiao-Dong; Du, Zhi-Zhi; Wu, Hai-Feng; Shen, Jian-Wei; Zhang, Xiao-feng
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论文出处: |
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年: |
2012
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卷: |
26 |
期: |
24 |
页: |
2309-2315 |
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发表期刊: |
NATURAL PRODUCT RESEARCH |
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影响因子: |
0.782
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摘要: |
Sixteen known compounds isolated from the whole plants of Euphorbia tangutica, including phorbol-13-actate (1) previously synthesised and obtained from a natural source for the first time, were evaluated in vitro against a panel of human cancer cell lines using the MTT method. Among them, ergosterol (6) exhibited significant cytotoxic activity against HL-60 cell line with an IC50 value of 3.3 mu M, and 3 beta,5 alpha-dihydroxy-15 beta-cinnamoyloxy-14-oxolathyra-6Z,12 E-diene (7) also displayed moderate activity. |
英文摘要: |
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