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论文 |
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论文题目: |
Diarylheptanoids and phenylphenalenones from Musa itinerans fruits
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论文题目英文: |
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作者: |
Liu, Fang; Zhang, Yu; Sun, Qian-Yun; Yang, Fu-Mei; Gu, Wei; Yang, Jun; Niu, Hong-Mei; Wang, Yue-Hu; Long, Chun-Lin
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论文出处: |
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年: |
2014
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卷: |
103 |
期: |
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页: |
171-177 |
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发表期刊: |
PHYTOCHEMISTRY |
第一作者所在部门: |
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影响因子: |
2.946
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摘要: |
Two diarylheptanoids, musaitinerins A and B, one heterodimeric phenylphenalenone musaitinerone and four known phenylphenalenones, identified as 4-hydroxy-2-methoxy-9-phenyl-1H-phenalen-1-one, musanolone E, hydroxyanigorufone and irenolone were isolated from the fruits of Musa itinerans Cheesm. Their structures were elucidated using spectroscopic analyses. The antimicrobial activity of these compounds was evaluated against Escherichia coli, Staphylococcus aureus and Candida albicans; the cytotoxic activity of these compounds was also evaluated against human erythromyeloblastoid leukemia (K562) and human alveolar carcinoma epithelial (A549) cell lines, respectively. Musaitinerone and musanolone E exhibited weak effects against the A549 cell line, as compared with adriamycin. However, these two compounds did not exhibit any growth inhibition against 1(562 cells, S. aureus, E. coli or C. albicans. The other compounds were inactive against all of the tested cell lines and microorganisms, even at concentrations as high as 50 mu M. (c) 2014 Elsevier Ltd. All rights reserved. |
英文摘要: |
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