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论文 |
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论文题目: |
Bioactivities of Compounds from Elephantopus scaber, an Ethnomedicinal Plant from Southwest China
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论文题目英文: |
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作者: |
Wang, Jianjun; Li, Ping; Li, Baosai; Guo, Zhiyong; Kennelly, Edward J.; Long, Chunlin
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2014
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发表期刊: |
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE |
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摘要: |
Elephantopus scaber is an ethnomedicinal plant used by the Zhuang people in Southwest China to treat headaches, colds, diarrhea, hepatitis, and bronchitis. A new delta-truxinate derivative, ethyl, methyl 3,4,3',4'-tetrahydroxy-delta-truxinate (1), was isolated from the ethyl acetate extract of the entire plant, along with 4 known compounds. The antioxidant activity of these 5 compounds was determined by ABTS radical scavenging assay. Compound 1 was also tested for its cytotoxicity effect against HepG2 by MTT assay (IC50 = 60 mu M), and its potential anti-inflammatory, antibiotic, and antitumor bioactivities were predicted using target fishing method software. |
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