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论文 |
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论文题目: |
Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway
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论文题目英文: |
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作者: |
Chen, XQ; Zhao, SM; Wang, Z; Zeng, GZ; Huang, MB; Tan, NH
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论文出处: |
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年: |
2015
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卷: |
71 |
期: |
52 |
页: |
71-52 |
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TETRAHEDRON |
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摘要: |
Three new cyclic hexapeptides, named as rubicordins A-C (1-3), together with seven known ones (4-10) were isolated from the roots and rhizomes of Rubia cordifolia. Their structures were elucidated by spectroscopic analysis, and the cytotoxic and NF-kappa B signaling pathway activities were tested. The results indicated that 1-10 showed cytotoxicity against SGC-7901, A549 or Hela cancer cell lines, and 1-3 inhibited NF-kappa B signaling pathway. (C) 2015 Elsevier Ltd. All rights reserved. |
英文摘要: |
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